HCAIX-IN-7

CAT: 0804-HY-147665Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147665Size:1 Each
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Description
HCAIX-IN-7 (compound 6c) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 43.0, 410.6 nM for hCAI, hCAII, hCAIV, hCAIX, respectively[1].
CAS Number
[2451479-58-4]
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaix-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC2=C(OC(C=C2)=O)C=C1)/C=C/C3=CC=CC(F)=C3
Molecular Formula
C18H12FNO3
Molecular Weight
309.29
References & Citations
[1]Swain B, et al. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg Med Chem. 2020 Aug 1;28 (15) :115586.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA IX

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