hCAIX-IN-17

hCAIX-IN-17

• UNSPSC Description: hCA IX-IN-1 (Compound 6f) is a human carbonic anhydrase (hCA) inhibitor with Ki values of 331.4, 28.4, 9.4 and 17.8 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-1 shows anticancer activity[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hca-ix-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: NS(=O)(C1=CC=C(C=C1)NCCC(C2=CC3=C(C=C2)C=CC=C3)=O)=O
• Molecular Weight: 354.42
• References & Citations: [1]Elbadawi MM, et al. Development of 4-((3-oxo-3-phenylpropyl)amino)benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2022 Apr 27;238:114412.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported