hCAIX-IN-13

hCAIX-IN-13

• CAS Number: 2813334-66-4
• UNSPSC Description: hCAIX-IN-13 (Pt2) is an inhibitor of CAIX (arbonic anhydrase IX) with an IC50 value of 6.57 μM. hCAIX-IN-13 inhibits growth of cancer cells and induces cell apoptosis, it can be used for the research of cancer[1].
• Target Antigen: Apoptosis
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hcaix-in-13.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(CCCC(NCCC1=CC=C(S(=O)(N)=O)C=C1)=O)NC2=CC3=CC=C[N]4=C3C5=[N]([Pt+2]46[C-]7=C(C8=[N]6C=CC=C8)C=CC=C7)C=CC=C52.FC(F)(S(=O)([O-])=O)F
• Molecular Weight: 989.90
• References & Citations: [1]Yang J, et al. NIR phosphorescent cyclometalated platinum (II) complexes with CAIX targeted and nuclear penetration as potent anticancer theragnostic agents. Eur J Med Chem. 2022 Aug 31;243:114702.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported