hCAIX-IN-18

• UNSPSC Description:

  hCAIX-IN-18 (compound 30) is an inhibitor of carbonic anhydrase (CA), with Kis of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for hCAI, hCAII, hCAIX, hCAXII, respectively. hCAIX-IN-18 can be used for cancer research[1].

• Target Antigen:

  Carbonic Anhydrase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hcaix-in-18.html

• Solubility:

  DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C)

• Smiles:

  ClC1=CC=C(/C(N2CCN(C3=CC=C(S(=O)(N)=O)C=C3)CC2)=N\O)C=C1

• Molecular Weight:

  394.88

• References & Citations:

  [1]1. Peerzada MN, et al. Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors. ACS Med Chem Lett. 2023 May 8;14(6):810-819.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2925261-76-1