HDAC-IN-35

• UNSPSC Description:

  HDAC-IN-35 (Compound 14) is a potent, selective HDAC and VEGFR-2 inhibitor, with IC50 values of 0.166 and 13.2 μM for HDAC6 and VEGFR-2, respectively[1].

• Target Antigen:

  HDAC; VEGFR

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics;Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hdac-in-35.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NO)/C=C/C1=CC=C(C=C1)NC(NC2=CC=C(C(C(F)(F)F)=C2)Cl)=O

• Molecular Weight:

  399.75

• References & Citations:

  [1]Szu Lee, et al. Effect of phenylurea hydroxamic acids on histone deacetylase and VEGFR-2. Bioorg Med Chem. 2021 Nov 15;50:116454.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported