COX-2-IN-13

• UNSPSC Description:

  COX-2-IN-13 (compound 13e) is a potent and selective inhibitor of COX-2 with an IC50 of 0.98 μM. COX-2-IN-13 is an anti-inflammatory agent. COX-2-IN-13 shows safety in-vivo acute toxicity study[1].

• Target Antigen:

  COX

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cox-2-in-13.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=CC=C(C=C1)C(CC2CC(N(C2=O)C3=CC=C(C=C3)S(N)(=O)=O)=O)=O

• Molecular Weight:

  386.42

• References & Citations:

  [1]Jan MS, et al. Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents. Eur J Med Chem. 2020;186:111863.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2987588-45-2