COX-2-IN-13

CAT: 0804-HY-146371Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-146371Size:1 Each
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Description
COX-2-IN-13 (compound 13e) is a potent and selective inhibitor of COX-2 with an IC50 of 0.98 μM. COX-2-IN-13 is an anti-inflammatory agent. COX-2-IN-13 shows safety in-vivo acute toxicity study[1].
CAS Number
[2987588-45-2]
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-2-in-13.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C=C1)C(CC2CC(N(C2=O)C3=CC=C(C=C3)S(N)(=O)=O)=O)=O
Molecular Formula
C19H18N2O5S
Molecular Weight
386.42
References & Citations
[1]Jan MS, et al. Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents. Eur J Med Chem. 2020;186:111863.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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