COX-2-IN-2

• Description :

  COX-2-IN-2 is a selective and inducible COX2 inhibitor with an IC50 of 0.24 μM. COX-2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities.

• UNSPSC :

  12352005

• Target :

  COX

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/1-_4-fluorophenyl_-5-[4-_methylsulfonyl_phenyl]-pyrazole-3-carbonitrile.html

• Purity :

  99.53

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  N#CC1=NN(C2=CC=C(F)C=C2)C(C3=CC=C(S(=O)(C)=O)C=C3)=C1

• Molecular Formula :

  C17H12FN3O2S

• Molecular Weight :

  341.36

• References & Citations :

  [1]Tsuji K, et al. Studies on anti-inflammatory agents. IV. Synthesis and pharmacological properties of 1,5-diarylpyrazoles and related derivatives. Chem Pharm Bull (1997), 45 (6), 987-995.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  COX-2

• CAS Number :

  [134729-13-8]