COX-2-IN-1

CAT: 0804-HY-U00275Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-U00275Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

COX-2-IN-1 is potent and slective COX-2 inhibitor with an IC50 of 3.9 μM.

CAS Number

787623-48-7

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/1-_4-Sulfamylphenyl_-3-trifluoromethyl-5-_7-chloroindol-3-yl_-2-pyrazoline.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(N2N=C(C(F)(F)F)CC2C3=CNC4=C3C=CC=C4Cl)C=C1)(N)=O

Molecular Formula

C18H14ClF3N4O2S

Molecular Weight

442.84

References & Citations

[1]Reddy MV, et al. Design, synthesis, and biological evaluation of 1- (4-sulfamylphenyl) -3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors. Bioorg Med Chem. 2008 Apr 1;16 (7) :3907-16.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

COX-2

Related Products

Catalog	Name
HY-159561	COX-1-IN-2
HY-146161	COX-2/NO-IN-1
HY-115967	COX-1/2-IN-2
HY-115966	COX-1/2-IN-1
HY-146704	COX-2/sEH-IN-1
HY-159158	COX-1/2-IN-8
HY-162761	COX-1/2-IN-9
HY-155764	COX-1/2-IN-4
HY-163187	COX-2/LOX-IN-1
HY-155768	COX-1/2-IN-5

Alternative Products

Catalog	Name
MBS5803131	COX-2/NO-IN-1
GTR19239148-01	COX-1-IN-2
M26018-01	COX-2-IN-1
T61865-01	COX-1/2-IN-2
GTR19187365-01	COX-1/2-IN-1
TBS2121	Cyclooxygenase (COX-1, COX-2) Inhibition Assay
T209627-01	INOS/COX-2-IN-1
T209071-01	COX-2/NLRP3-IN-1
T205462-01	EGFR/COX-2-IN-1
T62103-01	COX-2/PI3K-IN-1

COX-2-IN-1

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