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COX-2-IN-20

CAT: 0804-HY-147809Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147809Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
COX-2-IN-20 (Compound 5d) is a selective and orally active COX-2 inhibitor with an IC50 of 17.9 nM. COX-2-IN-20 shows anti-inflammatory activity[1].
CAS Number
2529451-43-0
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-2-in-20.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN(C2=CC=C(F)C=C2)C(CCl)=N1)OC
Molecular Formula
C11H9ClFN3O2
Molecular Weight
269.66
References & Citations
[1]Li SM, et al. New methyl 5- (halomethyl) -1-aryl-1H-1,2,4-triazole-3-carboxylates as selective COX-2 inhibitors and anti-inflammatory agents: Design, synthesis, biological evaluation, and docking study. Bioorg Chem. 2020 Nov;104:104333.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-1; COX-2

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