MT-7

• Description :

  MT-7 is a potent mitotic inhibitor. MT-7 shows antiproliferative activity. MT-7 induces cell cycle arrest at G2/M phase. MT-7 induces specific, reversible mitotic arrest and inhibits the polymerization of cellular microtubules[1].

• UNSPSC :

  12352005

• Target :

  Microtubule/Tubulin

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Cytoskeleton

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mt-7.html

• Smiles :

  O=C1N(C2=C(C3=C1C=CC=C3)N=C4N2C=CC=C4)CC5=CC=C(C=C5)OC

• Molecular Formula :

  C22H17N3O2

• Molecular Weight :

  355.39

• References & Citations :

  [1]Zhang Z, et al. MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules. Invest New Drugs. 2010 Dec;28 (6) :715-28.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [946507-08-0]