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MT-7

CAT: 0804-HY-122249Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-122249Size:1 Each
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Description
MT-7 is a potent mitotic inhibitor. MT-7 shows antiproliferative activity. MT-7 induces cell cycle arrest at G2/M phase. MT-7 induces specific, reversible mitotic arrest and inhibits the polymerization of cellular microtubules[1].
CAS Number
946507-08-0
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mt-7.html
Smiles
O=C1N(C2=C(C3=C1C=CC=C3)N=C4N2C=CC=C4)CC5=CC=C(C=C5)OC
Molecular Formula
C22H17N3O2
Molecular Weight
355.39
References & Citations
[1]Zhang Z, et al. MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules. Invest New Drugs. 2010 Dec;28 (6) :715-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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