MT-1207

• UNSPSC Description:

  MT-1207 is an orally active and selective adrenergic α1 and 5-HT2A receptor antagonist. MT-1207 shows IC501A, α1B, α1D and 5-HT2A, respectively. MT-1207 achieves an effective blood pressure (BP) reduction in the 2K2C rat model without damaging renal function. MT-1207 is a potent multitarget inhibitor with the potential for vasodilatation research[1].

• Target Antigen:

  5-HT Receptor; Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/mt-1207.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  C1(SN=C2N3CCN(CCCCN4N=NC5=C4C=CC=C5)CC3)=C2C=CC=C1.Cl

• Molecular Weight:

  428.98

• References & Citations:

  [1]Peng Wang, et al. Discovery of MT-1207: A Novel, Potent Multitarget Inhibitor as a Promising Clinical Candidate for the Treatment of Hypertension. J Med Chem. 2024 Jul 5.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported

• CAS Number:

  1610794-70-1