HCAIX-IN-2

• Description :

  HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the Ki values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively[1].

• UNSPSC :

  12352005

• Target :

  Carbonic Anhydrase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/hcaix-in-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=CC(N2C(C(N/N=C/C3=CC=NC=C3)=O)=NN(C2=N1)C4=CC=C(C=C4)S(N)(=O)=O)=O

• Molecular Formula :

  C19H16N8O4S

• Molecular Weight :

  452.45

• References & Citations :

  [1]Mohamed A Said, et al. Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2020 Jan 1;185:111843.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CA II; CA I; CA IX; CA XII

• CAS Number :

  [2389034-45-9]