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HCAIX-IN-2

CAT: 0804-HY-146207Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146207Size:1 Each
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Description
HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the Ki values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively[1].
CAS Number
2389034-45-9
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaix-in-2.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(N2C(C(N/N=C/C3=CC=NC=C3)=O)=NN(C2=N1)C4=CC=C(C=C4)S(N)(=O)=O)=O
Molecular Formula
C19H16N8O4S
Molecular Weight
452.45
References & Citations
[1]Mohamed A Said, et al. Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2020 Jan 1;185:111843.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II; CA I; CA IX; CA XII

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