HCAIX-IN-2

• Description:

  HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the Ki values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively[1].

• UNSPSC:

  12352005

• Target:

  Carbonic Anhydrase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hcaix-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=CC(N2C(C(N/N=C/C3=CC=NC=C3)=O)=NN(C2=N1)C4=CC=C(C=C4)S(N)(=O)=O)=O

• Molecular Formula:

  C19H16N8O4S

• Molecular Weight:

  452.45

• References & Citations:

  [1]Mohamed A Said, et al. Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2020 Jan 1;185:111843.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CA II; CA I; CA IX; CA XII

• CAS Number:

  [2389034-45-9]