HCAIX-IN-1

HCAIX-IN-1

• CAS Number: 2389034-65-3
• UNSPSC Description: HCAIX-IN-1 (compound 21e) is a potent and selective HCAIX inhibitor with KIs of 694.9, 126.6, 3.3, 9.8 nM for hCA I, hCA II, hCA IX, hCA XII, respectively[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hcaix-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC=C(C=C1)NC(NC2=NN(C(N)=N2)C3=CC=C(C=C3)S(N)(=O)=O)=O
• Molecular Weight: 403.42
• References & Citations: [1]Said MA,et al. Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2020 Jan 1;185:111843.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported