ROS inducer 4

• UNSPSC Description:

  ROS inducer 4 (compound TE3) is a mitochondrial inhibitor. ROS inducer 4 causes a series of mitochondria-related physiological changes in tumors, such as mitochondrial fragmentation, explosive generation and accumulation of ROS, decreased mitochondrial membrane potential, decreased ATP content, and activation of ROS-mediated apoptotic signaling in mitochondria[1].

• Target Antigen:

  Apoptosis; Mitochondrial Metabolism; Reactive Oxygen Species

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ros-inducer-4.html

• Smiles:

  O=C(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H]([C@@H](/C=C/[C@H](C)C(C)C)C)CC[C@@]4([H])[C@@]3(OO5)C=C[C@@]25C1)CC[P+](C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8.[Br-]

• Molecular Weight:

  825.89

• References & Citations:

  [1]Liu P, et al. Mitochondrial targeted modification and anticancer mechanism of natural product ergosterol peroxide. Bioorg Chem. 2024 Jul 31;151:107688.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2959444-40-5