Autophagy-IN-4

• UNSPSC Description:

  Autophagy-IN-4 (Compound 34) is an autophagy inhibitor, with an EC50 of 0.5 μM and a LD50 of 27 μM for U2OS cells[1].

• Target Antigen:

  Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/autophagy-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=CC=C2C(N=C3CCCCC3=C2NCCN4CCN(CC4)C)=C1

• Molecular Weight:

  358.91

• References & Citations:

  [1]Wang et al. Synthesis of improved lysomotropic autophagy inhibitors. J Med Chem. 2015 Apr 9;58(7):3025-35.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1411646-44-0