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AChE-IN-15

CAT: 0804-HY-146039Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146039Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AChE-IN-15 (Compound 3d) is a reversible human acetylcholinesterase (huAChE) (IC50=6.8 μM) and human butyrylcholinesterase (huBChE) (IC50=16.1 μM) inhibitor. AChE-IN-15 shows significant antioxidant potency, AChE-IN-15 can be used for the research of Alzheimer’s disease[1].
CAS Number
2242792-25-0
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-15.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1=CC=C(C2=CC(C3=C(O)C=C(OC(N(CC)C)=O)C=C3O2)=O)C=C1)N(CC)C
Molecular Formula
C23H24N2O7
Molecular Weight
440.45
References & Citations
[1]Zhipei Sang, et al. Apigenin-rivastigmine hybrids as multi-target-directed liagnds for the treatment of Alzheimer's disease. Eur J Med Chem. 2020 Feb 1;187:111958.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE