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AChE/BChE-IN-15

CAT: 0804-HY-149484Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149484Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AChE/BChE-IN-15 (Compound 6d) is an AChE/BChE inhibitor, with IC50s of 20 nM and 220 nM respectively. AChE/BChE-IN-15 binds to both catalytic anionic site (CAS) and peripheral anionic site (PAS) in the active sites of AChE and BChE. AChE/BChE-IN-15 can be used for research of Alzheimer’s disease[1].
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-bche-in-15.html
Solubility
10 mM in DMSO
Smiles
O=C1C(OCCCCCCCCN2N=NC=C2CNC3=CC=C4N=CC=NC4=C3)=CC(C5=C1C=CC=C5)=O
Molecular Formula
C29H30N6O3
Molecular Weight
510.59
References & Citations
[1]Paptawan Suwanhom, et al. Novel Lawsoneuinoxaline Hybrids as New Dual Binding Site Acetylcholinesterase Inhibitors. ACS Omega 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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