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AChE-IN-80

CAT: 0804-HY-170658Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-170658Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AChE-IN-80 (Compound 1) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-80 can inhibit inflammation and the production of reactive oxygen species (ROS) in vitro- cultured neurons and microglia, trigger autophagy responses, and block the propagation of β-amyloid (Aβ) fibrils. AChE-IN-80 possesses antioxidant activity and neuroprotective effects and can be used in the study of Alzheimer's disease[1].
UNSPSC
12352005
Target
Amyloid-β; Autophagy; Reactive Oxygen Species (ROS)
Related Pathways
Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
Neuroscience-Neurodegeneration
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
NC(C1=CC(OC(N(C)CC)=O)=CC=C1)=S
Molecular Formula
C11H14N2O2S
Molecular Weight
238.31
References & Citations
[1]Sestito S, et al. Design, synthesis and biological evaluation of new H2S-releasing rivastigmine derivatives as neuroprotective molecules[J]. European Journal of Medicinal Chemistry, 2025, 283: 117175.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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