Antimalarial agent 7

• Description:

  Antimalarial agent 7 is a potent inhibitor of PfATP4. PfATP4 is an essential ion pump on the parasite surface. Antimalarial agent 7 has the potential for the research of human malaria parasite, Plasmodium falciparum[1].

• UNSPSC:

  12352005

• Target:

  Na+/K+ ATPase; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Membrane Transporter/Ion Channel

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antimalarial-agent-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC (C) (OC1=CC=C (C=C1) C2=NN=C3C=NC=C (N32) OCC (C4=CC (F) =C (C=C4) F) O) C

• Molecular Formula:

  C23H22F2N4O3

• Molecular Weight:

  440.44

• References & Citations:

  [1]Tse EG, et al. An Open Drug Discovery Competition: Experimental Validation of Predictive Models in a Series of Novel Antimalarials. J Med Chem. 2021;64 (22) :16450-16463.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Plasmodium

• CAS Number:

  2756414-77-2