LSD1-IN-13 (hydrochloride)
CAT:
804-HY-144675A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
LSD1-IN-13 (hydrochloride)
- CAS Number: 2170347-90-5
- UNSPSC Description: LSD1-IN-13 hydrochloride (compound 7e) is an orally active and potent LSD1 inhibitor, with an IC50 of 24.43 nM. LSD1-IN-13 hydrochloride can activate CD86 expression, with an EC50 of 470 nM. LSD1-IN-13 hydrochloride induces differentiation of AML (acute myeloid leukemia) cell lines[1].
- Target Antigen: Histone Demethylase
- Type: Reference compound
- Related Pathways: Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/lsd1-in-13-hydrochloride.html
- Solubility: 10 mM in DMSO
- Smiles: O=S(N1CCC2=C1C=CC([C@H]3[C@H](NCC4CCNCC4)C3)=C2)(C5=CC=CC=C5)=O.[H]Cl
- Molecular Weight: 448.02
- References & Citations: [1]Li C, et al. Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors. J Med Chem. 2022 Mar 10;65(5):4335-4349.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported