LSD1-IN-6

LSD1-IN-6

• CAS Number: 2035912-43-5
• UNSPSC Description: LSD1-IN-6 (Compound 4m) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1].
• Target Antigen: Histone Demethylase
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/lsd1-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: OC1=C(O)C=C(Br)C(/C=C/C2=CC=C(/C(N)=N/O)C=C2)=C1
• Molecular Weight: 349.18
• References & Citations: [1]Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported