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LSD1-IN-23

CAT: 0804-HY-152032Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152032Size:1 Each
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Description
LSD1-IN-23 is a competitive/non-competitive mixed inhibitor of lysine specific demethylase 1 (LSD1) . LSD1-IN-23 has LSD1 inhibitory activity with an IC50 value of 0.58 μM. LSD1-IN-23 can be used for the research of neuroblastoma (NB) [1].
CAS Number
3033660-66-8
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lsd1-in-23.html
Solubility
10 mM in DMSO
Smiles
O=S(NC(C=CC(Br)=C1)=C1C2=NNN=N2)(C3=CC=C(C=C3)C4=CC=C(C=C4)Cl)=O
Molecular Formula
C19H13BrClN5O2S
Molecular Weight
490.76
References & Citations
[1]Catherine M Mills, et al. Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma. Eur J Med Chem. 2022 Dec 15;244:114818.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1

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