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LSD1-IN-16

CAT: 0804-HY-144757Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144757Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LSD1-IN-16 (compound 4b) is a potent LSD1 inhibitor. LSD1-IN-16 can inhibit LSD1-CoREST, MAO-A and MAO-B, with IC50 values of 0.015, 0.024, and 0.366 μM, respectively. LSD1-IN-16 displays cell growth arrest in prostate cancer LNCaP cells, with an IC50 of 15.2 μM[1].
UNSPSC
12352005
Target
Histone Demethylase; Monoamine Oxidase
Type
Reference compound
Related Pathways
Epigenetics; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lsd1-in-16.html
Solubility
10 mM in DMSO
Smiles
NC1CC1C2=CC=C(C=C2)NC(C3=CC=CC(C4=CC=CS4)=C3)=O
Molecular Formula
C20H18N2OS
Molecular Weight
334.43
References & Citations
[1]Fioravanti R, et al. Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :973-985.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1; MAO-A; MAO-B

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