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SOS1-IN-12

CAT: 0804-HY-144965Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144965Size:1 Each
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Description
SOS1-IN-12 is a potent son of sevenless homolog 1 (SOS1) inhibitor with a Ki of 0.11 nM for SOS1 and an IC50 of 47 nM for pERK. SOS1-IN-13 can be used for researching anticancer[1].
CAS Number
2654741-56-5
UNSPSC
12352005
Target
Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sos1-in-12.html
Solubility
10 mM in DMSO
Smiles
CC1=NN=C(C2=CC(N3CCNCC3)=CC=C21)N[C@@H](C4=CC=CC(C(F)(F)F)=C4C)C
Molecular Formula
C23H26F3N5
Molecular Weight
429.48
References & Citations
[1]Matthew Arnold Marx, et al. Sos1 inhibitors. WO2021127429A1 (compound 6-4)
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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