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STING agonist-8

CAT: 0804-HY-144168Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144168Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STING agonist-8 is a potent STING agonist with an EC50 of 27 nM in THP1-Dual KI-hSTING-R232 cells (WO2021239068A1, compound 5-AB) [1].
CAS Number
2745723-90-2
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sting-agonist-8.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCC6CNC6)C=C(C(N)=O)C=C5C7=CN=C(C8=CC(C)=NN8CC)N=C74
Molecular Formula
C41H46N14O4
Molecular Weight
798.90
References & Citations
[1]Heterocyclic compounds as sting modulators. WO2021239068A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported