RIPK1-IN-9

• UNSPSC Description:

  RIPK1-IN-9 (example 45), a dihydronaphthyridone compound, is a potent and selective RIPK1 inhibitor. RIPK1-IN-9 inhibits U937 cell (IC50=2 nM) and L929 cell (IC50=1.3 nM)[1].

• Target Antigen:

  RIP kinase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ripk1-in-9.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(N=CC(C3=CC4=NC(N)=NN4C=C3)=C2)CCN1CC5=CC(F)=CC=C5OC6CCCC6

• Molecular Weight:

  472.51

• References & Citations:

  [1]Fusheng Zhou, et al. Dihydronaphthyridone compounds, their preparation and pharmaceutical uses. WO2021160109A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2682889-57-0