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TAS2R14 agonist-2

CAT: 0804-HY-153265-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153265-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TAS2R14 agonist-2 (compound 28.1) is a potent and selective TAS2R14 agonist with an EC50 value of 72 nM. TAS2R14 agonist-2 reveals marked selectivity over a panel of 24 non-bitter taste human G protein-coupled receptors. TAS2R14 agonist-2 can be used for the studies of asthma or chronic obstructive pulmonary disease[1].
CAS Number
2883007-69-8
UNSPSC
12352005
Target
Taste Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tas2r14-agonist-2.html
Purity
99.91
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
FC(F)(C1=CC(C)=NC(NC2=C(C3=NN=NN3)C=CC=C2)=N1)F
Molecular Formula
C13H10F3N7
Molecular Weight
321.26
References & Citations
[1]Waterloo L, et al. Discovery of 2-Aminopyrimidines as Potent Agonists for the Bitter Taste Receptor TAS2R14. J Med Chem. 2023 Mar 9;66 (5) :3499-3521.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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