GPR35 agonist 2

• Description :

  GPR35 agonist 2 (compound 11) is a potent agonist of GPR35, with EC50s of 26 and 3.2 nM in the β-arrestin and Ca2+ release assay, respectively[1].

• UNSPSC :

  12352005

• Target :

  Arrestin; GPR35

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/gpr35-agonist-2.html

• Purity :

  98.61

• Solubility :

  DMSO : 25 mg/mL (ultrasonic)

• Smiles :

  O=C(O)C1=CC=C(/C=C(SC(NC2=CC=CC=C2F)=N3)\C3=O)C=C1

• Molecular Formula :

  C17H11FN2O3S

• Molecular Weight :

  342.34

• References & Citations :

  [1]Thimm D, et, al. 6-Bromo-8- (4-[ (3) H]methoxybenzamido) -4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35. J Med Chem. 2013 Sep 12; 56 (17) : 7084-99.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [494191-73-0]