GPR35 agonist 2

GPR35 agonist 2

• CAS Number: 494191-73-0
• UNSPSC Description: GPR35 agonist 2 (compound 11) is a potent agonist of GPR35, with EC50s of 26 and 3.2 nM in the β-arrestin and Ca2+ release assay, respectively[1].
• Target Antigen: Arrestin; GPR35
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/gpr35-agonist-2.html
• Solubility: DMSO : 25 mg/mL (ultrasonic)
• Smiles: O=C(O)C1=CC=C(/C=C(SC(NC2=CC=CC=C2F)=N3)\C3=O)C=C1
• Molecular Weight: 342.34
• References & Citations: [1]Thimm D, et, al. 6-Bromo-8-(4-[(3)H]methoxybenzamido)-4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35. J Med Chem. 2013 Sep 12; 56(17): 7084-99.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported