RegisterLogin

LP-284

CAT: 0804-HY-139453ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-139453ASize:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
LP-284 is a potent DNA alkylating agent that kills solid tumours. LP-284 can be used in the studies of hematologic cancers with compromised DNA repair, such as mantle cell lymphoma (MCL) [1][2].
CAS Number
[2412580-47-1]
UNSPSC
12352211
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lp-284.html
Solubility
10 mM in DMSO
Smiles
CC(C1(CC1)[C@@](O)(C)C2=O)=C3C2=CC(C)=C3CN(C(N)=O)O
Molecular Formula
C16H20N2O4
Molecular Weight
304.34
References & Citations
[1]Zhou J, et al. MCL-319 LP-284 - A Highly Potent Small Molecule Targeting Mantle Cell Lymphoma. Clin Lymphoma Myeloma Leuk. 2022 Oct;22 Suppl 2:S396. |[2]Zhou J, et al. The Positive Enantiomer of a Novel Chiral DNA Alkylating Agent Exhibits Nanomolar Potency in Hematologic Cancers. Blood, 2021, 138: 3991.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

Related Products

CatalogName
HY-159482SBN-284
HY-107777A-01LLY-284
HY-19987-01BML-284
HY-146697IHMT-TRK-284
HY-174313Antibacterial agent 284
HY-178937Anticancer agent 284
HY-W999602CRBN ligand-284
HY-19987ABML-284 (hydrochloride)
HY-19987R-01BML-284 (Standard)
HY-111455-01LP-211

Alternative Products

CatalogName
T60706-01LP-284
MBS131522BML-284 (BML 284; BML284)
T88928-01SBN-284
MBS5756871LLY-284
BUP15472-01BML-284
A2299-80AApolipoprotein Lp (a) (Apo Lp-a)
030400LPA (Apolipoprotein (a), LP, Lp (a) )
KAI-044Lp (a)
M22979-01BML-284 HCL
RM-S041584-01Sildenafil Impurity 284

Popular Products