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LLY-284

CAT: 0804-HY-107777A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-107777A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LLY-284 is the diastereomer of LLY-283 with much less active. LLY-283 is a potent inhibitor of PRMT5. LLY-284 has the potential for the research of cancer diseases[1].
CAS Number
2226515-75-7
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lly-284.html
Purity
99.11
Solubility
DMSO : 9.52 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@H]([C@@H]1O)[C@](O[C@]1([H])[C@H](C2=CC=CC=C2)O)([H])N3C4=NC=NC(N)=C4C=C3
Molecular Formula
C17H18N4O4
Molecular Weight
342.35
References & Citations
[1]Bonday ZQ, et al. LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity. ACS Med Chem Lett. 2018;9 (7) :612-617.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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A24348-5LLY-284 5mg
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