SBN-284

• Target:

  NOD-like Receptor (NLR) |||Cholinesterase (ChE)

• Related Pathways:

  Immunology/Inflammation|||Neuroscience

• Bioactivity:

  SBN-284 (compound 3x) acts as a dual inhibitor of cholinesterases (Cholinesterases) and NLRP3 inflammasomes, demonstrating blood-brain barrier permeability. It exhibits IC50 values of 0.37, 0.31, and 0.29 ?M against EeAChE, hAChE, and eqBChE respectively, and an EC50 value of 1 ?M against NLRP3. SBN-284 is utilized in Alzheimers disease research.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C