Methotrexate γ-Methyl Ester

• Description :

  Methotrexate γ-Methyl Ester (Methotrexate 5-methyl ester) is an impurity of the folate antagonist Methotrexate (HY-14519) [1].

• Product Name Alternative :

  Methotrexate 5-methyl ester; γ-EMTX

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335

• Target :

  Antifolate

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/methotrexate-γ-methyl-ester.html

• Purity :

  98.30

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OC)CC[C@@H](C(O)=O)NC(C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3N=C2)C)C=C1)=O

• Molecular Formula :

  C21H24N8O5

• Molecular Weight :

  468.47

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]James J Fort, et al. Transport and degradation characteristics of methotrexate diallsyl ester prodrugs across tape-stripped hairless mouse skin. Int J Pharm. 1993, 100 (1-3) : 233-239.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [67022-39-3]