Methotrexate diethyl ester

• Description :

  Methotrexate diethyl ester is a potent DHFR inhibitor. Methotrexate diethyl ester can be used in the research of T.cruzi infection and leukemia[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H301-H315-H319-H341-H360

• Target :

  Dihydrofolate reductase (DHFR)

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer; Infection

• Smiles :

  NC1=NC(N)=NC2=C1N=C(CN(C3=CC=C(C=C3)C(N[C@H](C(OCC)=O)CCC(OCC)=O)=O)C)C=N2

• Molecular Formula :

  C24H30N8O5

• Molecular Weight :

  510.55

• Precautions :

  P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P405-P501

• References & Citations :

  [1]McCormack JJ. Dihydrofolate reductase inhibitors as potential drugs. Med Res Rev. 1981 Fall;1 (3) :303-31.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound

• Clinical Information :

  No Development Reported

• CAS Number :

  [43170-88-3]