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TrxR-IN-2

CAT: 0804-HY-132972Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-132972Size:1 Each
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Description
TrxR-IN-2, a potential thioredoxin reductase (TrxR) inhibitor, represents a promising candidate drug for the chemoresearch of drug-resistant hepatocellular carcinoma.
CAS Number
2866261-50-7
UNSPSC
12352005
Target
TrxR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/trxr-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C1C=CCCN1C(/C=C/C2=NC(C)=C(/C=C/C(N3CCC=CC3=O)=O)N=C2C)=O
Molecular Formula
C22H22N4O4
Molecular Weight
406.43
References & Citations
[1]Qian J, et al. A Derivative of Piperlongumine and Ligustrazine as a Potential Thioredoxin Reductase Inhibitor in Drug-Resistant Hepatocellular Carcinoma. J Nat Prod. 2021 Nov 21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported