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TrxR-IN-3

CAT: 0931-T60453-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T60453-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2445565-58-0
Target
Others
Related Pathways
Others
Bioactivity
TrxR-IN-3 (Compound 2c) is an effective TrxR inhibitor that exhibits strong antiproliferative activities against five human cancer cell lines, particularly breast tumor cells. It increases ROS levels, induces apoptosis by regulating apoptosis-related protein expression in breast cancer cells, and promotes autophagosome and autolysosome formation by enhancing LC3-II and Beclin-1 expression and reducing LC3-I and p62 protein expression [1].
Smiles
C(=C\1/C(=O)C=CCC1)\C2=CC=C(OC(F)(F)F)C=C2
Molecular Formula
C14H11F3O2
Molecular Weight
268.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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