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TrxR-IN-5

CAT: 0931-T61647-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T61647-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, ROS
Related Pathways
Immunology/Inflammation, Others
Bioactivity
TrxR-IN-5 (compound 4f) is an effective inhibitor of thioredoxin reductase (TrxR) with an IC50 of 0.16 μM. TrxR-IN-5 increases reactive oxygen species (ROS) levels, reverses TGFβ1-induced epithelial-mesenchymal transition, and exhibits anti-proliferative and anti-metastatic effects against human breast cancer cells.
Smiles
O=C1C=CCC/C1=C/C2=CC=C(OC3=CC=C(/C=C4CCC=CC\4=O)C=C3)C=C2
Molecular Formula
C26H22O3
Molecular Weight
382.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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