Antimalarial agent 53

• Description :

  Antimalarial agent 53 is an antimalarial agent. Antimalarial agent 53 blocks protein synthesis by inhibiting the cytoplasmic ribosomes of malaria parasites, exhibiting potent antimalarial activity (IC50 = 3.9 nM) and good selectivity. Antimalarial agent 53 has no cross resistance and good safety. Antimalarial agent 53 can be used for research on malaria[1].

• UNSPSC :

  12352005

• Target :

  Parasite

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  O=C(NC1=CC(NN2CCN(C)CC2)=CC=C1O)C3=CC(OC4=CC(C(F)(F)F)=CC=N4)=CC=C3

• Molecular Formula :

  C24H24F3N5O3

• Molecular Weight :

  487.47

• References & Citations :

  [1]Bravo P, et al. A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum. Angew Chem Int Ed Engl. 2025 Oct 20:e202514085.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported