TUG-1387

• Description :

  TUG-1387 is a control compound for the FFA4 antagonists AH-7614 (HY-19996) and TUG-1506 without inhibitroy activity against FFA4. TUG-1387 can be used as a negative control for FFA4 functional assessments[1].

• UNSPSC :

  12352005

• Target :

  Free Fatty Acid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/tug-1387.html

• Purity :

  98.67

• Solubility :

  10 mM in DMSO|DMSO : ≥ 2mg/mL

• Smiles :

  CC1=CC=C(C(NC2C(C=CC=C3)=C3OC4=C2C=CC=C4)=O)C=C1

• Molecular Formula :

  C21H17NO2

• Molecular Weight :

  315.37

• References & Citations :

  [1]Watterson KR, et al. Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4. Mol Pharmacol. 2017 Jun;91 (6) :630-641.|[2]Milligan G, et al. FFA4/GPR120: Pharmacology and Therapeutic Opportunities. Trends Pharmacol Sci. 2017 Sep;38 (9) :809-821.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [6319-64-8]