TRV-1387

• UNSPSC Description:

  TRV-1387 is a benzofurazan that inhibits the aggregation of tau and amyloid-β[1].

• Target Antigen:

  Amyloid-β; Tau Protein

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/trv-1387.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC(F)(C(C1=CC=CC(C2=CC3=NON=C3C(N4CCC(CC4)N5CCCC5)=C2)=C1)O)F

• Molecular Weight:

  446.47

• References & Citations:

  [1]Rauch JN, et al. Interactions between Microtubule-Associated Protein Tau (MAPT) and Small Molecules. Cold Spring Harb Perspect Med. 2017 Jul 5;7(7):a024034.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1569645-63-1