TRV-1387

• Description :

  TRV-1387 is a benzofurazan that inhibits the aggregation of tau and amyloid-β[1].

• CAS Number :

  [1569645-63-1]

• UNSPSC :

  12352005

• Target :

  Amyloid-β; Tau Protein

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/trv-1387.html

• Solubility :

  10 mM in DMSO

• Smiles :

  FC(F)(C(C1=CC=CC(C2=CC3=NON=C3C(N4CCC(CC4)N5CCCC5)=C2)=C1)O)F

• Molecular Formula :

  C23H25F3N4O2

• Molecular Weight :

  446.47

• References & Citations :

  [1]Rauch JN, et al. Interactions between Microtubule-Associated Protein Tau (MAPT) and Small Molecules. Cold Spring Harb Perspect Med. 2017 Jul 5;7 (7) :a024034.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported