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TUG-2208

CAT: 0804-HY-163350-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-163350-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TUG-2208 (compound 42a) is a GPR84 agonist (pEC50=8.98) with low lipophilicity and good solubility, in vitro permeability and microsomal stability[1].
UNSPSC
12352005
Target
GPR84
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tug-2208.html
Purity
98.09
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1)C=C(O)C=C1C(C=N2)=CC=C2OC3=CC=CC=C3
Molecular Formula
C16H12N2O3
Molecular Weight
280.28
References & Citations
[1]Ieremias L, et al., Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 Agonists. J Med Chem. 2024 Feb 21.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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