Products for Research Use Only
RegisterLogin

TUG-424

CAT: 0804-HY-14363-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14363-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity[1]. TUG-424 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
1082058-99-8
UNSPSC
12352005
Hazard Statement
H319, H410
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tug-424.html
Purity
99.68
Solubility
10 mM in DMSO|DMSO : ≥ 10mg/mL
Smiles
OC(CCC(C=C1)=CC=C1C#CC2=C(C)C=CC=C2)=O
Molecular Formula
C18H16O2
Molecular Weight
264.32
Precautions
H319, H410
References & Citations
[1]Discovery of Potent and Selective Agonists for the Free Fatty Acid Receptor 1 (FFA1/GPR40), a Potential Target for the Treatment of Type II Diabetes J. Med. Chem., 2008, 51 (22), pp 7061-7064|[2]Christiansen E, et al. Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA (1) /GPR40), a potential target for the treatment of type II diabetes. J Med Chem. 2008 Nov 27;51 (22) :7061-4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P991461AMG-424
HY-176039TUG-2181
HY-129136TUG-1387
HY-148418-01TUG-499
HY-163350-01TUG-2208
HY-100881-01TUG-891
HY-112813-01TUG-1375
HY-15697-01TUG-770
HY-117787TUG-905
HY-123297-01TUG-469

Alternative Products

CatalogName
B7499-5TUG 424
GTR19202965-01TUG-424
E8ER1918-28TUG
BA5326-10TUG-1375
BA5331-10TUG-469
A3895-50TUG-770
BA5332-5TUG-499
10R-1832TUG antibody
ZEC51607-01TUG-891
GAA31964-01TUG-1387

Popular Products