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TUG-770

CAT: 0804-HY-15697-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15697-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TUG-770 is a potent, selective and orally active GPR40/FFA1 agonist with an EC50 of 6 nM for human FFA1. TUG-770 shows a high selectivity for FFA1 over FFA2, FFA3, FFA4, PPARγ, other receptors, transporters, and enzymes. TUG-770 can be uesd for type 2 diabetes research[1]. TUG-770 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
1402601-82-4
UNSPSC
12352005
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tug-770.html
Purity
99.07
Solubility
DMSO : ≥ 100 mg/mL
Smiles
FC1=C(CCC(O)=O)C=CC(C#CC2=C(CC#N)C=CC=C2)=C1
Molecular Formula
C19H14FNO2
Molecular Weight
307.32
References & Citations
[1]Christiansen E, et al. Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes. ACS Med Chem Lett. 2013 May 9;4 (5) :441-445.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
A3895-25TUG-770
MBS130055-01TUG 770
A12994-100TUG-770 100mg
A12994-500TUG-770 500mg
A12994-5TUG-770 5mg
A12994-50TUG-770 50mg
A12994-1TUG-770 1mg
A12994-25TUG-770 25mg
A12994-10TUG-770 10mg
A12994-10mM-DTUG-770 10mM * 1mL in DMSO

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