Antimalarial agent 20

• UNSPSC Description:

  Antimalarial agent 20 (Compound 49c) is an antimalarial agent with an IC50 of 0.6 nM against P. falciparum NF54 parasite strain in the NF54 albumax assay[1].

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antimalarial-agent-20.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](CC1=CC=CC=C1)[C@H](O)CN[C@@H](C2=CC=CC=C2)C)C3=CC=C(C(N4CCN(C)CC4)=O)C=C3

• Molecular Weight:

  514.66

• References & Citations:

  [1]Ciana CL, et al. Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffold. Bioorg Med Chem Lett. 2013 Feb 1;23(3):658-62.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4