MDL 27399

• Description:

  MDL 27399 is an inhibitor of human neutrophil cathepsin G (Ki = 7 μM) . MDL 27399 can be used for research of inflammatory diseases[1].

• UNSPSC:

  12352005

• Target:

  Cathepsin

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/mdl-27399.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C ([C@@H] (NC ([C@H]1N (CCC1) C ([C@@H] (NC ([C@@H] (NC (CCC (OC) =O) =O) C) =O) C) =O) =O) CC2=CC=CC=C2) OC

• Molecular Formula:

  C26H36N4O8

• Molecular Weight:

  532.59

• References & Citations:

  [1]N.S. Doherty, et al. Novel inhibitors of polymorphonuclear neutrophil (PMN) elastase and cathepsin G: Evaluation in vitro of their potential for the treatment of inflammatory connective tissue damage. International Journal of Immunopharmacology. Volume 12, Issue 7, 1990, Pages 787-795

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  131374-22-6