MDL 27399

• UNSPSC Description:

  MDL 27399 is an inhibitor of human neutrophil cathepsin G (Ki = 7 μM). MDL 27399 can be used for research of inflammatory diseases[1].

• Target Antigen:

  Cathepsin

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/mdl-27399.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC(CCC(OC)=O)=O)C)=O)C)=O)=O)CC2=CC=CC=C2)OC

• Molecular Weight:

  532.59

• References & Citations:

  [1]N.S. Doherty, et al. Novel inhibitors of polymorphonuclear neutrophil (PMN) elastase and cathepsin G: Evaluation in vitro of their potential for the treatment of inflammatory connective tissue damage. International Journal of Immunopharmacology. Volume 12, Issue 7, 1990, Pages 787-795

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  131374-22-6