MDL 27399

• Description :

  MDL 27399 is an inhibitor of human neutrophil cathepsin G (Ki = 7 μM) . MDL 27399 can be used for research of inflammatory diseases[1].

• UNSPSC :

  12352005

• Target :

  Cathepsin

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/mdl-27399.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC(CCC(OC)=O)=O)C)=O)C)=O)=O)CC2=CC=CC=C2)OC

• Molecular Formula :

  C26H36N4O8

• Molecular Weight :

  532.59

• References & Citations :

  [1]N.S. Doherty, et al. Novel inhibitors of polymorphonuclear neutrophil (PMN) elastase and cathepsin G: Evaluation in vitro of their potential for the treatment of inflammatory connective tissue damage. International Journal of Immunopharmacology. Volume 12, Issue 7, 1990, Pages 787-795

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [131374-22-6]