MDL 201112

• Description :

  MDL 201112 is a carbocyclic nucleoside. MDL 201112 can decrease TNF-α production and inhibit MHC class II Ia+ antigen expression. MDL 201112 can be used for the research of inflammation and immunology[1].

• UNSPSC :

  12352005

• Target :

  MHC; TNF Receptor

• Related Pathways :

  Apoptosis; Immunology/Inflammation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  NC1=NC=NC2=C1N=CN2[C@@H]3C[C@H](O)CC3

• Molecular Formula :

  C10H13N5O

• Molecular Weight :

  219.24

• References & Citations :

  [1]Edwards CK 3rd, et al. Effect of the carbocyclic nucleoside analogue MDL 201,112 on inhibition of interferon-gamma-induced priming of Lewis (LEW/N) rat macrophages for enhanced respiratory burst and MHC class II Ia+ antigen expression. J Leukoc Biol. 1994 Aug;56 (2) :133-44.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  MHC II

• CAS Number :

  [142130-73-2]