MDL 105212A

• Description:

  MDL 105212A is a potent and orally active nonpeptide neurokinin receptor (NK-1/NK-2) tachykinin receptor antagonist. MDL 105212A can be used for the researches of inflammation, immunology and neurological disease, such as asthma[1].

• UNSPSC:

  12352005

• Target:

  Neurokinin Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Smiles:

  NC(C(CC1)(C2=CC=CC=C2)CCN1CC[C@@]3(C4=CC(Cl)=C(Cl)C=C4)CN(C(C5=CC(OC)=C(OC)C(OC)=C5)=O)CC3)=O.Cl

• Molecular Formula:

  C34H40Cl3N3O5

• Molecular Weight:

  677.06

• References & Citations:

  [1]Kudlacz EM, et al. In vitro and in vivo characterization of MDL 105,212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist. J Pharmacol Exp Ther. 1996 May;277 (2) :840-51.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  NK1R; NK2R

• CAS Number:

  [167261-60-1]