MDL-29951

CAT: 0804-HY-16312-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-16312-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
MDL-29951 is a novel glycine antagonist of NMDA receptor activation, with Ki of 0.14 μM for [3H]glycine binding in vitro and in vivo.
CAS Number
[130798-51-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mdl-29951.html
Purity
99.17
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(O)CCC1=C(C(O)=O)NC2=C1C(Cl)=CC(Cl)=C2
Molecular Formula
C12H9Cl2NO4
Molecular Weight
302.11
Precautions
H302, H315, H319, H335
References & Citations
[1]Baron BM, et al. Potent indole- and quinoline-containing N-methyl-D-aspartate antagonists acting at the strychnine-insensitive glycine binding site. J Pharmacol Exp Ther. 1992 Sep;262 (3) :947-56.|[2]Wright SW, et al. 3- (2-carboxyethyl) -4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site. Bioorg Med Chem Lett. 2003 Jun 16;13 (12) :2055-8.|[3]Harden TK. Enigmatic GPCR finds a stimulating drug. Sci Signal. 2013 Oct 22;6 (298) :pe34.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor

Related Products

CatalogName
HY-P1017MDL 29913
HY-105517MDL 27032
HY-105488MDL 201112
HY-105483MDL 43291
HY-100621-01MDL 72527
HY-112252MDL 73811
HY-105528MDL-25637
HY-105340MDL 27266
HY-141426-01MDL-860
HY-118264MDL-100240

Alternative Products

CatalogName
MBS130125-01MDL-29951
TRC-M199790-250MGMDL 29951
A13729-50MDL 29951 50mg
A13729-200MDL 29951 200mg
A13729-10MDL 29951 10mg
A13729-1MDL 29951 1mg
A13729-5MDL 29951 5mg
A13729-25MDL 29951 25mg
A13729-100MDL 29951 100mg
TBI4537-5MGMDL-29951, GPR17 agonist

Popular Products