BMS-903452

• UNSPSC Description:

  BMS-903452 is a potent and selective GPR119 agonist for diabetes research[1].

• Target Antigen:

  GPR119

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/bms-903452.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=CN=C(N2CCC(OC3=CC(N(C4=CC=C(S(=O)(C)=O)C=C4F)C=C3Cl)=O)CC2)N=C1

• Molecular Weight:

  513.37

• References & Citations:

  [1]Wacker DA, et al. Discovery of 5-chloro-4-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)oxy)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyridin-2(1H)-one (BMS-903452), an antidiabetic clinical candidate targeting GPR119. J Med Chem. 2014 Sep 25;57(18):7499-508.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 1

• CAS Number:

  1339944-47-6