BMS-903452

• Description :

  BMS-903452 is a potent and selective GPR119 agonist for diabetes research[1].

• UNSPSC :

  12352005

• Target :

  GPR119

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/bms-903452.html

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC1=CN=C(N2CCC(OC3=CC(N(C4=CC=C(S(=O)(C)=O)C=C4F)C=C3Cl)=O)CC2)N=C1

• Molecular Formula :

  C21H19Cl2FN4O4S

• Molecular Weight :

  513.37

• References & Citations :

  [1]Wacker DA, et al. Discovery of 5-chloro-4- ((1- (5-chloropyrimidin-2-yl) piperidin-4-yl) oxy) -1- (2-fluoro-4- (methylsulfonyl) phenyl) pyridin-2 (1H) -one (BMS-903452), an antidiabetic clinical candidate targeting GPR119. J Med Chem. 2014 Sep 25;57 (18) :7499-508.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [1339944-47-6]