BMS-903452

• Description :

  BMS-903452 is a potent and selective GPR119 agonist with an EC50 of 14 nM, indicated for the treatment of acute and chronic rodent diabetes. GPR119 is mainly expressed in pancreatic b cells and gastrointestinal endocrine cells. BMS-903452 shows no significant inhibitory effect on 9 cytochrome P450 enzymes (IC50 > 40 μM), does not activate PXR (EC50 > 50 μM), and is not toxic to liver (HEPG2) cell lines.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  513.37

• Molecular Formula :

  C21H19Cl2FN4O4S

• Notes :

  Research use only, not for human use.

• Receptor :

  GPR

• CAS Number :

  1339944-47-6