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ABBV-4083

CAT: 0804-HY-111757Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-111757Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABBV-4083 is an analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity[1].
CAS Number
[1809266-03-2]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ABBV-4083.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@H](C)O[C@](OC[C@H]([C@@H](CC)OC(C[C@H]([C@@H]([C@H]([C@@H](CC=O)C[C@H]2C)O[C@]3([H])O[C@H](C)[C@@H](O[C@]4([H])O[C@@H](C)[C@H](OCC5=CC=C(F)C=C5)[C@@](O)(C)C4)[C@H](N(C)C)[C@H]3O)C)O)=O)/C=C(C)/C=C/C2=O)([H])[C@H](OC)[C@@H]1OC
Molecular Formula
C53H82FNO17
Molecular Weight
1024.21
References & Citations
[1]von Geldern TW, et al. Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity. PLoS Negl Trop Dis. 2019 Feb 28;13 (2) :e0007159.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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